HCSGD entry for ASXL2
1. General information
| Official gene symbol | ASXL2 |
|---|---|
| Entrez ID | 55252 |
| Gene full name | additional sex combs like 2 (Drosophila) |
| Other gene symbols | ASXH2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0035360 | Positive regulation of peroxisome proliferator activated receptor signaling pathway | IDA | biological_process |
| GO:0042975 | Peroxisome proliferator activated receptor binding | IDA | molecular_function |
| GO:0045600 | Positive regulation of fat cell differentiation | IDA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0594865279 | 0.9368192584 | 0.5284322983 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0158068338 |
| GSE13712_SHEAR | Up | 0.4281909282 |
| GSE13712_STATIC | Up | 0.0896985244 |
| GSE19018 | Down | -0.1744694519 |
| GSE19899_A1 | Up | 0.2255520310 |
| GSE19899_A2 | Up | 0.1008204765 |
| PubMed_21979375_A1 | Up | 0.7166098796 |
| PubMed_21979375_A2 | Up | 0.4778600909 |
| GSE35957 | Down | -0.1713532022 |
| GSE36640 | Down | -0.0365724180 |
| GSE54402 | Up | 0.3000215225 |
| GSE9593 | Up | 0.0484914048 |
| GSE43922 | Up | 0.3990187123 |
| GSE24585 | Down | -0.1177812000 |
| GSE37065 | Up | 0.2649809016 |
| GSE28863_A1 | Up | 0.7551256440 |
| GSE28863_A2 | Up | 0.5951909476 |
| GSE28863_A3 | Down | -0.4568235083 |
| GSE28863_A4 | Down | -0.1036441858 |
| GSE48662 | Down | -0.0335487983 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT000818 | Microarray | Functional MTI (Weak) | 18362358 |
| hsa-miR-15a-5p | MIMAT0000068 | MIRT000819 | Microarray | Functional MTI (Weak) | 18362358 |
| hsa-miR-502-3p | MIMAT0004775 | MIRT037979 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-326 | MIMAT0000756 | MIRT043632 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-378a-5p | MIMAT0000731 | MIRT044010 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT046874 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-15a-5p | MIMAT0000068 | NA | hsa-miR-15a | 18362358 | |||
| hsa-miR-16-5p | MIMAT0000069 | NA | hsa-miR-16 | 18362358 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
