HCSGD entry for OGFOD1
1. General information
| Official gene symbol | OGFOD1 |
|---|---|
| Entrez ID | 55239 |
| Gene full name | 2-oxoglutarate and iron-dependent oxygenase domain containing 1 |
| Other gene symbols | TPA1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005506 | Iron ion binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0016706 | Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | IEA | molecular_function |
| GO:0031418 | L-ascorbic acid binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0485507883 | 0.9577663235 | 0.4864270209 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5524497581 |
| GSE13712_SHEAR | Up | 0.3952061420 |
| GSE13712_STATIC | Up | 0.2771821415 |
| GSE19018 | Down | -0.2863366848 |
| GSE19899_A1 | Up | 0.2766649459 |
| GSE19899_A2 | Up | 0.4983640055 |
| PubMed_21979375_A1 | Up | 0.5412959311 |
| PubMed_21979375_A2 | Up | 0.3457105524 |
| GSE35957 | Down | -0.1021539022 |
| GSE36640 | Up | 0.3051827382 |
| GSE54402 | Up | 0.1929750323 |
| GSE9593 | Up | 0.1230907371 |
| GSE43922 | Up | 0.2471757874 |
| GSE24585 | Down | -0.3940938389 |
| GSE37065 | Up | 0.0129540089 |
| GSE28863_A1 | Down | -0.0068301332 |
| GSE28863_A2 | Up | 0.1099839657 |
| GSE28863_A3 | Down | -0.4344335667 |
| GSE28863_A4 | Up | 0.2231643997 |
| GSE48662 | Up | 0.2198607425 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Vitamin C | DB00126 | NUTR00001 | APRD00084 | EXPT00568 | DB09541 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019747 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020601 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025269 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028422 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040452 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046787 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
