HCSGD entry for PPP2R1B
1. General information
| Official gene symbol | PPP2R1B |
|---|---|
| Entrez ID | 5519 |
| Gene full name | protein phosphatase 2, regulatory subunit A, beta |
| Other gene symbols | PP2A-Abeta PR65B |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0045121 | Membrane raft | IDA | cellular_component |
| GO:0060561 | Apoptotic process involved in morphogenesis | IMP | biological_process |
| GO:2001241 | Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0569839558 | 0.8858843319 | 0.5188082670 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1838946817 |
| GSE13712_SHEAR | Up | 0.3725648504 |
| GSE13712_STATIC | Up | 0.3024850321 |
| GSE19018 | Up | 0.1613732617 |
| GSE19899_A1 | Up | 0.2030950012 |
| GSE19899_A2 | Up | 0.6369102599 |
| PubMed_21979375_A1 | Up | 0.9674317602 |
| PubMed_21979375_A2 | Up | 0.3445255085 |
| GSE35957 | Up | 0.1936774378 |
| GSE36640 | Down | -0.3658904706 |
| GSE54402 | Up | 0.1550415143 |
| GSE9593 | Down | -0.1164377638 |
| GSE43922 | Up | 0.1822854148 |
| GSE24585 | Up | 0.1155489131 |
| GSE37065 | Up | 0.5813059024 |
| GSE28863_A1 | Down | -0.2084288346 |
| GSE28863_A2 | Up | 0.0352065074 |
| GSE28863_A3 | Down | -0.3494223982 |
| GSE28863_A4 | Down | -0.1091566144 |
| GSE48662 | Down | -0.1242043927 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022210 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025691 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042516 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051305 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
