HCSGD entry for SEC61A2
1. General information
| Official gene symbol | SEC61A2 |
|---|---|
| Entrez ID | 55176 |
| Gene full name | Sec61 alpha 2 subunit (S. cerevisiae) |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002474 | Antigen processing and presentation of peptide antigen via MHC class I | TAS | biological_process |
| GO:0002479 | Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | TAS | biological_process |
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0042590 | Antigen processing and presentation of exogenous peptide antigen via MHC class I | TAS | biological_process |
| GO:0043022 | Ribosome binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2332226131 | 0.8740577828 | 0.9169010306 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1807601737 |
| GSE13712_SHEAR | Up | 0.0600343542 |
| GSE13712_STATIC | Up | 0.0329796543 |
| GSE19018 | Down | -0.0211957737 |
| GSE19899_A1 | Up | 0.0829319368 |
| GSE19899_A2 | Up | 0.2432752854 |
| PubMed_21979375_A1 | Down | -0.1978648613 |
| PubMed_21979375_A2 | Up | 0.4115836205 |
| GSE35957 | Up | 0.0248915549 |
| GSE36640 | Up | 0.2597491177 |
| GSE54402 | Up | 0.2580761375 |
| GSE9593 | Up | 0.0065161375 |
| GSE43922 | Up | 0.0241155323 |
| GSE24585 | Down | -0.0085917237 |
| GSE37065 | Up | 0.2271763471 |
| GSE28863_A1 | Down | -0.1196824976 |
| GSE28863_A2 | Up | 0.4339851601 |
| GSE28863_A3 | Down | -0.6789307075 |
| GSE28863_A4 | Up | 0.0699544221 |
| GSE48662 | Up | 0.0515053141 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029682 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-182-5p | MIMAT0000259 | MIRT047197 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051301 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
