HCSGD entry for PNPO
1. General information
| Official gene symbol | PNPO |
|---|---|
| Entrez ID | 55163 |
| Gene full name | pyridoxamine 5'-phosphate oxidase |
| Other gene symbols | PDXPO |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004733 | Pyridoxamine-phosphate oxidase activity | IEA TAS | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006766 | Vitamin metabolic process | TAS | biological_process |
| GO:0006767 | Water-soluble vitamin metabolic process | TAS | biological_process |
| GO:0008615 | Pyridoxine biosynthetic process | IEA | biological_process |
| GO:0010181 | FMN binding | IEA | molecular_function |
| GO:0042816 | Vitamin B6 metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6747548991 | 0.0185304206 | 0.9999902473 | 0.2666376297 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5454736256 |
| GSE13712_SHEAR | Down | -0.0014491362 |
| GSE13712_STATIC | Up | 0.2802343781 |
| GSE19018 | Down | -0.8371644140 |
| GSE19899_A1 | Down | -0.4782458588 |
| GSE19899_A2 | Down | -0.6302724626 |
| PubMed_21979375_A1 | Down | -0.9817669936 |
| PubMed_21979375_A2 | Down | -0.3628907361 |
| GSE35957 | Up | 0.1016074965 |
| GSE36640 | Up | 1.1761818675 |
| GSE54402 | Down | -0.0012710507 |
| GSE9593 | Up | 0.2065207295 |
| GSE43922 | Down | -0.5703939014 |
| GSE24585 | Up | 0.0875345005 |
| GSE37065 | Down | -0.0962496984 |
| GSE28863_A1 | Down | -0.7285801297 |
| GSE28863_A2 | Down | -0.1520125115 |
| GSE28863_A3 | Down | -0.8532191457 |
| GSE28863_A4 | Up | 0.0272422374 |
| GSE48662 | Down | -0.0722623553 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Riboflavin Monophosphate | DB03247 | EXPT01458 |
| Beta-Mercaptoethanol | DB03345 | EXPT02882 | DB03131 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028520 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-18a-5p | MIMAT0000072 | MIRT050711 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
