HCSGD entry for THAP1


1. General information

Official gene symbolTHAP1
Entrez ID55145
Gene full nameTHAP domain containing, apoptosis associated protein 1
Other gene symbolsDYT6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001935Endothelial cell proliferationIMPbiological_process
GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0006351Transcription, DNA-templatedIMPbiological_process
GO:0006355Regulation of transcription, DNA-templatedIMPbiological_process
GO:0007049Cell cycleIEAbiological_process
GO:0007346Regulation of mitotic cell cycleIMPbiological_process
GO:0008270Zinc ion bindingIDAmolecular_function
GO:0016605PML bodyIEAcellular_component
GO:0043565Sequence-specific DNA bindingIDA IMPmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02757582540.53857059000.38505214851.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3880862718
GSE13712_SHEARUp0.2772746652
GSE13712_STATICUp0.0907550389
GSE19018Down-0.5571600304
GSE19899_A1Up0.6576225818
GSE19899_A2Up0.4369516001
PubMed_21979375_A1Up1.2647734913
PubMed_21979375_A2Up0.6791908197
GSE35957Up0.0851946697
GSE36640Up0.2018655743
GSE54402Up0.8798272729
GSE9593Down-0.2274872114
GSE43922Up0.5320274722
GSE24585Down-0.0754280817
GSE37065Up0.0157717893
GSE28863_A1Down-0.3136059544
GSE28863_A2Down-0.1118538750
GSE28863_A3Down-0.8666896026
GSE28863_A4Up0.1659049445
GSE48662Down-0.0431394486

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.