HCSGD entry for WRAP53
1. General information
| Official gene symbol | WRAP53 |
|---|---|
| Entrez ID | 55135 |
| Gene full name | WD repeat containing, antisense to TP53 |
| Other gene symbols | DKCB3 TCAB1 WDR79 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003723 | RNA binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005697 | Telomerase holoenzyme complex | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0015030 | Cajal body | IDA | cellular_component |
| GO:0032203 | Telomere formation via telomerase | IMP | biological_process |
| GO:0051973 | Positive regulation of telomerase activity | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3375713043 | 0.3944625128 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0507941897 |
| GSE13712_SHEAR | Down | -0.1381468404 |
| GSE13712_STATIC | Down | -0.2497338837 |
| GSE19018 | Up | 0.0252959777 |
| GSE19899_A1 | Up | 0.2196057744 |
| GSE19899_A2 | Up | 0.2152799036 |
| PubMed_21979375_A1 | Up | 0.9698896933 |
| PubMed_21979375_A2 | Up | 0.1008904410 |
| GSE35957 | Down | -0.4213657554 |
| GSE36640 | Down | -0.4293351006 |
| GSE54402 | Up | 0.1672731884 |
| GSE9593 | Down | -0.3763176526 |
| GSE43922 | Up | 0.3948093729 |
| GSE24585 | Up | 0.0108971396 |
| GSE37065 | Down | -0.1087083139 |
| GSE28863_A1 | Down | -0.2404969441 |
| GSE28863_A2 | Down | -0.2113080024 |
| GSE28863_A3 | Up | 0.1602310442 |
| GSE28863_A4 | Up | 0.0937274922 |
| GSE48662 | Down | -0.2462987809 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022742 | Proteomics | Functional MTI (Weak) | 18668037 |
| hsa-miR-455-3p | MIMAT0004784 | MIRT037886 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-3p | MIMAT0004672 | MIRT038551 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
