HCSGD entry for PIWIL2


1. General information

Official gene symbolPIWIL2
Entrez ID55124
Gene full namepiwi-like RNA-mediated gene silencing 2
Other gene symbolsCT80 HILI PIWIL1L mili
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000966RNA 5'-end processingISSbiological_process
GO:0003729MRNA bindingIEAmolecular_function
GO:0005737CytoplasmISScellular_component
GO:0005844PolysomeIEAcellular_component
GO:0007126MeiosisIEAbiological_process
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0007283SpermatogenesisIEAbiological_process
GO:0030718Germ-line stem cell maintenanceISSbiological_process
GO:0031047Gene silencing by RNAISSbiological_process
GO:0033391Chromatoid bodyISScellular_component
GO:0034584PiRNA bindingIDA ISSmolecular_function
GO:0034587PiRNA metabolic processISSbiological_process
GO:0043046DNA methylation involved in gamete generationISSbiological_process
GO:0043186P granuleISScellular_component
GO:0045727Positive regulation of translationISSbiological_process
GO:0048477OogenesisISSbiological_process
GO:0060903Positive regulation of meiosis IIEAbiological_process
GO:0071546Pi-bodyISScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.56776454160.78268825650.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0443011027
GSE13712_SHEARDown-0.0035995820
GSE13712_STATICDown-0.0237575265
GSE19018Up0.0466826730
GSE19899_A1Up0.0581649306
GSE19899_A2Up0.1378762965
PubMed_21979375_A1Down-0.1344651399
PubMed_21979375_A2Down-0.0280347816
GSE35957Down-0.0074191101
GSE36640Down-0.2018595417
GSE54402Down-0.0596984197
GSE9593Down-0.0028971401
GSE43922Up0.0147879319
GSE24585Down-0.0083897774
GSE37065Up0.1388499524
GSE28863_A1Up0.6544137747
GSE28863_A2Down-0.0120680576
GSE28863_A3Up0.2102120041
GSE28863_A4Up0.0050382568
GSE48662Down-0.0559835808

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.