HCSGD entry for MARC2
1. General information
| Official gene symbol | MARC2 |
|---|---|
| Entrez ID | 54996 |
| Gene full name | mitochondrial amidoxime reducing component 2 |
| Other gene symbols | MOSC2 RP11-270A6.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005739 | Mitochondrion | IDA ISS | cellular_component |
| GO:0005741 | Mitochondrial outer membrane | IEA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IEA | cellular_component |
| GO:0005777 | Peroxisome | IEA | cellular_component |
| GO:0008940 | Nitrate reductase activity | IDA | molecular_function |
| GO:0030151 | Molybdenum ion binding | IDA | molecular_function |
| GO:0030170 | Pyridoxal phosphate binding | IEA | molecular_function |
| GO:0042126 | Nitrate metabolic process | IDA | biological_process |
| GO:0043546 | Molybdopterin cofactor binding | IDA | molecular_function |
| GO:0051410 | Detoxification of nitrogen compound | NAS | biological_process |
| GO:0055114 | Oxidation-reduction process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6768919608 | 0.0358281600 | 0.9999902473 | 0.3575484653 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0465434554 |
| GSE13712_SHEAR | Down | -0.0417237709 |
| GSE13712_STATIC | Up | 0.2797671286 |
| GSE19018 | Up | 0.3281213729 |
| GSE19899_A1 | Down | -0.1132140045 |
| GSE19899_A2 | Down | -0.9904905912 |
| PubMed_21979375_A1 | Down | -1.1660635145 |
| PubMed_21979375_A2 | Down | -0.4574531089 |
| GSE35957 | Up | 0.0912180659 |
| GSE36640 | Up | 0.4692422167 |
| GSE54402 | Down | -1.5632405713 |
| GSE9593 | Down | -0.3755330881 |
| GSE43922 | Down | -1.3724783040 |
| GSE24585 | Down | -0.0244230863 |
| GSE37065 | Down | -0.0313121544 |
| GSE28863_A1 | Up | 0.1270814418 |
| GSE28863_A2 | Up | 0.5454217455 |
| GSE28863_A3 | Down | -0.2231028064 |
| GSE28863_A4 | Up | 0.0477167041 |
| GSE48662 | Down | -0.0404802413 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020826 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029722 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
