HCSGD entry for TIPIN


1. General information

Official gene symbolTIPIN
Entrez ID54962
Gene full nameTIMELESS interacting protein
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000076DNA replication checkpointIMPbiological_process
GO:0000077DNA damage checkpointIEAbiological_process
GO:0000790Nuclear chromatinIDAcellular_component
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDA IEAcellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0006974Cellular response to DNA damage stimulusIEAbiological_process
GO:0007049Cell cycleIEAbiological_process
GO:0007067MitosisIEAbiological_process
GO:0008284Positive regulation of cell proliferationIMPbiological_process
GO:0009411Response to UVIEAbiological_process
GO:0031573Intra-S DNA damage checkpointIMPbiological_process
GO:0033262Regulation of nuclear cell cycle DNA replicationTASbiological_process
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0044770Cell cycle phase transitionIMPbiological_process
GO:0048478Replication fork protectionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.90837440830.00510190720.99999024730.1458059718

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0882352358
GSE13712_SHEARDown-0.2016135961
GSE13712_STATICUp0.6497988913
GSE19018Down-0.8114495067
GSE19899_A1Down-0.4790154668
GSE19899_A2Down-0.9344882263
PubMed_21979375_A1Up0.1350730216
PubMed_21979375_A2Down-1.3920757342
GSE35957Down-1.6422698634
GSE36640Down-2.0393806073
GSE54402Up0.3631830649
GSE9593Down-0.8208962380
GSE43922Down-0.3033842033
GSE24585Down-0.1621874469
GSE37065Up0.1019939600
GSE28863_A1Down-0.1467599605
GSE28863_A2Down-0.0029611650
GSE28863_A3Up0.0538640269
GSE28863_A4Up0.1560444187
GSE48662Down-0.4945687865

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-484MIMAT0002174MIRT041905CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.