HCSGD entry for SSH3


1. General information

Official gene symbolSSH3
Entrez ID54961
Gene full nameslingshot protein phosphatase 3
Other gene symbolsSSH3L
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEAmolecular_function
GO:0003779Actin bindingIBAmolecular_function
GO:0004725Protein tyrosine phosphatase activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIBAcellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0006470Protein dephosphorylationIBAbiological_process
GO:0008064Regulation of actin polymerization or depolymerizationIBAbiological_process
GO:0008138Protein tyrosine/serine/threonine phosphatase activityIBA IEAmolecular_function
GO:0010591Regulation of lamellipodium assemblyIBAbiological_process
GO:0050770Regulation of axonogenesisIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.87617767940.08496618290.99999024730.5530155539

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1348768810
GSE13712_SHEARDown-0.2462490272
GSE13712_STATICDown-0.0753975171
GSE19018Up0.0291505472
GSE19899_A1Down-0.3597864373
GSE19899_A2Down-0.2560365356
PubMed_21979375_A1Down-0.7286966574
PubMed_21979375_A2Down-0.3593535718
GSE35957Up0.5156091353
GSE36640Up0.5111648268
GSE54402Down-0.4295830457
GSE9593Up0.2434711649
GSE43922Down-0.6205423823
GSE24585Up0.0370914474
GSE37065Down-0.0695893889
GSE28863_A1Up0.1253777972
GSE28863_A2Down-0.2058540996
GSE28863_A3Down-0.0224124219
GSE28863_A4Down-0.1766015888
GSE48662Up0.3979340852

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-346MIMAT0000773MIRT004229MicroarrayFunctional MTI (Weak)16822819
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.