HCSGD entry for DUS2L
1. General information
| Official gene symbol | DUS2L |
|---|---|
| Entrez ID | 54920 |
| Gene full name | dihydrouridine synthase 2-like, SMM1 homolog (S. cerevisiae) |
| Other gene symbols | DUS2 SMM1 URLC8 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003725 | Double-stranded RNA binding | IDA | molecular_function |
| GO:0004860 | Protein kinase inhibitor activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0006469 | Negative regulation of protein kinase activity | IDA | biological_process |
| GO:0017150 | TRNA dihydrouridine synthase activity | IEA | molecular_function |
| GO:0042325 | Regulation of phosphorylation | IDA | biological_process |
| GO:0042326 | Negative regulation of phosphorylation | IDA | biological_process |
| GO:0043086 | Negative regulation of catalytic activity | IDA | biological_process |
| GO:0045859 | Regulation of protein kinase activity | IDA | biological_process |
| GO:0050660 | Flavin adenine dinucleotide binding | IEA | molecular_function |
| GO:0050790 | Regulation of catalytic activity | IDA | biological_process |
| GO:0060548 | Negative regulation of cell death | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9755795828 | 0.0405840888 | 0.9999902473 | 0.3802230387 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1220784012 |
| GSE13712_SHEAR | Down | -0.1600523672 |
| GSE13712_STATIC | Up | 0.1985391044 |
| GSE19018 | Up | 0.0705754150 |
| GSE19899_A1 | Down | -0.1556931089 |
| GSE19899_A2 | Up | 0.1199310842 |
| PubMed_21979375_A1 | Up | 0.4579663222 |
| PubMed_21979375_A2 | Down | -0.3076768335 |
| GSE35957 | Down | -0.0955363569 |
| GSE36640 | Down | -0.2856869941 |
| GSE54402 | Down | -0.0402721744 |
| GSE9593 | Down | -0.4730924730 |
| GSE43922 | Down | -0.0186404925 |
| GSE24585 | Down | -0.6339607030 |
| GSE37065 | Down | -0.1389550886 |
| GSE28863_A1 | Down | -0.2527925618 |
| GSE28863_A2 | Down | -0.3666832653 |
| GSE28863_A3 | Down | -0.6486359953 |
| GSE28863_A4 | Up | 0.0683570363 |
| GSE48662 | Down | -0.0999815371 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-324-3p | MIMAT0000762 | MIRT042984 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
