HCSGD entry for WHSC1L1
1. General information
| Official gene symbol | WHSC1L1 |
|---|---|
| Entrez ID | 54904 |
| Gene full name | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| Other gene symbols | NSD3 pp14328 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IC IEA | cellular_component |
| GO:0005694 | Chromosome | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016571 | Histone methylation | IDA | biological_process |
| GO:0018022 | Peptidyl-lysine methylation | IDA | biological_process |
| GO:0018024 | Histone-lysine N-methyltransferase activity | IDA IEA | molecular_function |
| GO:0034968 | Histone lysine methylation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9560429581 | 0.1960599217 | 0.9999902473 | 0.8576268982 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1094631584 |
| GSE13712_SHEAR | Down | -0.1210454403 |
| GSE13712_STATIC | Down | -0.0641179244 |
| GSE19018 | Up | 0.0397232632 |
| GSE19899_A1 | Down | -0.1989311144 |
| GSE19899_A2 | Down | -0.3134018047 |
| PubMed_21979375_A1 | Down | -0.0156213152 |
| PubMed_21979375_A2 | Down | -0.1482166263 |
| GSE35957 | Down | -0.1543506370 |
| GSE36640 | Down | -0.1629114180 |
| GSE54402 | Up | 0.0373915013 |
| GSE9593 | Up | 0.0623572906 |
| GSE43922 | Down | -0.0501096433 |
| GSE24585 | Up | 0.3065295984 |
| GSE37065 | Down | -0.0114574042 |
| GSE28863_A1 | Down | -0.2821031787 |
| GSE28863_A2 | Down | -0.2496958201 |
| GSE28863_A3 | Down | -0.2790272999 |
| GSE28863_A4 | Down | -0.0157649697 |
| GSE48662 | Down | -0.0968250873 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT020035 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT021058 | Reporter assay;Other | Functional MTI | 21030878 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026836 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT031070 | Microarray | Functional MTI (Weak) | 19398721 |
| hsa-miR-196b-5p | MIMAT0001080 | MIRT042677 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-301a-3p | MIMAT0000688 | MIRT044223 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10b-5p | MIMAT0000254 | MIRT047495 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
