HCSGD entry for ELOVL2
1. General information
| Official gene symbol | ELOVL2 |
|---|---|
| Entrez ID | 54898 |
| Gene full name | ELOVL fatty acid elongase 2 |
| Other gene symbols | SSC2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006636 | Unsaturated fatty acid biosynthetic process | IEA | biological_process |
| GO:0009922 | Fatty acid elongase activity | IDA | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019432 | Triglyceride biosynthetic process | TAS | biological_process |
| GO:0033559 | Unsaturated fatty acid metabolic process | TAS | biological_process |
| GO:0034626 | Fatty acid elongation, polyunsaturated fatty acid | IDA | biological_process |
| GO:0035338 | Long-chain fatty-acyl-CoA biosynthetic process | TAS | biological_process |
| GO:0036109 | Alpha-linolenic acid metabolic process | TAS | biological_process |
| GO:0042761 | Very long-chain fatty acid biosynthetic process | IDA | biological_process |
| GO:0043651 | Linoleic acid metabolic process | TAS | biological_process |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9512416626 | 0.0001952395 | 0.9999902473 | 0.0248226415 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0412347326 |
| GSE13712_SHEAR | Down | -0.1143258591 |
| GSE13712_STATIC | Down | -0.0746952280 |
| GSE19018 | Down | -1.6453360009 |
| GSE19899_A1 | Down | -0.7877128043 |
| GSE19899_A2 | Down | -1.6754317064 |
| PubMed_21979375_A1 | Down | -2.5659834721 |
| PubMed_21979375_A2 | Down | -2.0899990151 |
| GSE35957 | Down | -0.3006739732 |
| GSE36640 | Down | -4.6852532827 |
| GSE54402 | Down | -4.3093524008 |
| GSE9593 | Down | -0.0846294204 |
| GSE43922 | Down | -2.4197331601 |
| GSE24585 | Down | -0.4439880355 |
| GSE37065 | Down | -0.0932407575 |
| GSE28863_A1 | Down | -0.0443101423 |
| GSE28863_A2 | Up | 1.6746530015 |
| GSE28863_A3 | Up | 0.2226867948 |
| GSE28863_A4 | Down | -0.1258746755 |
| GSE48662 | Down | -0.1516235481 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-10a-5p | MIMAT0000253 | MIRT025624 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029052 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-17-3p | MIMAT0000071 | MIRT050775 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
