HCSGD entry for RNF43
1. General information
| Official gene symbol | RNF43 |
|---|---|
| Entrez ID | 54894 |
| Gene full name | ring finger protein 43 |
| Other gene symbols | RNF124 URCC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005109 | Frizzled binding | IPI | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005635 | Nuclear envelope | IEA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0005887 | Integral component of plasma membrane | IDA | cellular_component |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016055 | Wnt signaling pathway | IEA | biological_process |
| GO:0016567 | Protein ubiquitination | IDA | biological_process |
| GO:0030178 | Negative regulation of Wnt signaling pathway | IMP | biological_process |
| GO:0038018 | Wnt receptor catabolic process | IDA | biological_process |
| GO:0042787 | Protein ubiquitination involved in ubiquitin-dependent protein catabolic process | IDA | biological_process |
| GO:0072089 | Stem cell proliferation | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8129823867 | 0.6883529767 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1353431786 |
| GSE13712_SHEAR | Down | -0.0704458570 |
| GSE13712_STATIC | Down | -0.0138141872 |
| GSE19018 | Up | 0.2753938401 |
| GSE19899_A1 | Up | 0.1251787047 |
| GSE19899_A2 | Down | -0.0682258080 |
| PubMed_21979375_A1 | Up | 0.0970785900 |
| PubMed_21979375_A2 | Down | -0.0067723211 |
| GSE35957 | Down | -0.1077643590 |
| GSE36640 | Up | 0.1813809147 |
| GSE54402 | Up | 0.0222449971 |
| GSE9593 | Down | -0.0750285059 |
| GSE43922 | Up | 0.0142106254 |
| GSE24585 | Down | -0.1036312459 |
| GSE37065 | Up | 0.0141392874 |
| GSE28863_A1 | Down | -0.0845763600 |
| GSE28863_A2 | Down | -0.0573139306 |
| GSE28863_A3 | Up | 0.1981225951 |
| GSE28863_A4 | Down | -0.0144570785 |
| GSE48662 | Down | -0.0293023966 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT019206 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
