HCSGD entry for TBC1D8B
1. General information
| Official gene symbol | TBC1D8B |
|---|---|
| Entrez ID | 54885 |
| Gene full name | TBC1 domain family, member 8B (with GRAM domain) |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005097 | Rab GTPase activator activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2641987728 | 0.1009952851 | 0.9587723563 | 0.6085233463 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4077621270 |
| GSE13712_SHEAR | Down | -0.6057588009 |
| GSE13712_STATIC | Down | -0.2018183517 |
| GSE19018 | Up | 0.4585156611 |
| GSE19899_A1 | Up | 0.3455855745 |
| GSE19899_A2 | Down | -0.1063391178 |
| PubMed_21979375_A1 | Down | -0.3754264874 |
| PubMed_21979375_A2 | Down | -0.3828153373 |
| GSE35957 | Down | -0.1501937501 |
| GSE36640 | Up | 0.9710904577 |
| GSE54402 | Down | -0.1948539951 |
| GSE9593 | Down | -0.0596813788 |
| GSE43922 | Up | 0.0685513349 |
| GSE24585 | Down | -0.0629680834 |
| GSE37065 | Down | -0.2692092276 |
| GSE28863_A1 | Up | 0.6821250547 |
| GSE28863_A2 | Up | 0.6353830049 |
| GSE28863_A3 | Down | -0.7242095716 |
| GSE28863_A4 | Up | 0.0230278423 |
| GSE48662 | Down | -0.1952296403 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018774 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020982 | Reporter assay;Other | Non-Functional MTI | 20584899 |
| hsa-miR-30e-5p | MIMAT0000692 | MIRT044147 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
