HCSGD entry for BCOR
1. General information
| Official gene symbol | BCOR |
|---|---|
| Entrez ID | 54880 |
| Gene full name | BCL6 corepressor |
| Other gene symbols | ANOP2 MAA2 MCOPS2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IEA IMP | biological_process |
| GO:0000415 | Negative regulation of histone H3-K36 methylation | IMP | biological_process |
| GO:0003714 | Transcription corepressor activity | IDA IEA IMP | molecular_function |
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007507 | Heart development | IMP | biological_process |
| GO:0008134 | Transcription factor binding | IPI | molecular_function |
| GO:0030502 | Negative regulation of bone mineralization | IMP | biological_process |
| GO:0031072 | Heat shock protein binding | IDA | molecular_function |
| GO:0031519 | PcG protein complex | IDA | cellular_component |
| GO:0035518 | Histone H2A monoubiquitination | IDA | biological_process |
| GO:0042476 | Odontogenesis | IMP | biological_process |
| GO:0042826 | Histone deacetylase binding | IPI | molecular_function |
| GO:0044212 | Transcription regulatory region DNA binding | IMP | molecular_function |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA IMP | biological_process |
| GO:0051572 | Negative regulation of histone H3-K4 methylation | IMP | biological_process |
| GO:0060021 | Palate development | IMP | biological_process |
| GO:0065001 | Specification of axis polarity | IMP | biological_process |
| GO:0070171 | Negative regulation of tooth mineralization | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0437145777 | 0.8998656510 | 0.4656460542 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3973270662 |
| GSE13712_SHEAR | Up | 0.4200446092 |
| GSE13712_STATIC | Up | 0.2694588450 |
| GSE19018 | Up | 0.2939557614 |
| GSE19899_A1 | Up | 0.1526689724 |
| GSE19899_A2 | Up | 0.4659344832 |
| PubMed_21979375_A1 | Up | 0.6804421782 |
| PubMed_21979375_A2 | Up | 0.6053644131 |
| GSE35957 | Down | -0.2692032851 |
| GSE36640 | Down | -0.2851326355 |
| GSE54402 | Down | -0.0371042605 |
| GSE9593 | Down | -0.0309209654 |
| GSE43922 | Up | 0.4161228165 |
| GSE24585 | Up | 0.8975810786 |
| GSE37065 | Up | 0.1893775541 |
| GSE28863_A1 | Up | 0.1093666336 |
| GSE28863_A2 | Up | 0.0283771252 |
| GSE28863_A3 | Up | 0.1361133769 |
| GSE28863_A4 | Up | 0.0276383060 |
| GSE48662 | Down | -0.2777931462 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-425-5p | MIMAT0003393 | MIRT016675 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024747 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026271 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039646 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-598-3p | MIMAT0003266 | MIRT040487 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-346 | MIMAT0000773 | MIRT042721 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-328-3p | MIMAT0000752 | MIRT043816 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044816 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-191-5p | MIMAT0000440 | MIRT045797 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT045914 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7f-5p | MIMAT0000067 | MIRT051395 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051754 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052180 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052633 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
