HCSGD entry for TRPM7
1. General information
| Official gene symbol | TRPM7 |
|---|---|
| Entrez ID | 54822 |
| Gene full name | transient receptor potential cation channel, subfamily M, member 7 |
| Other gene symbols | ALSPDC CHAK CHAK1 LTRPC7 TRP-PLIK |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001726 | Ruffle | IEA | cellular_component |
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0005216 | Ion channel activity | IEA | molecular_function |
| GO:0005262 | Calcium channel activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016340 | Calcium-dependent cell-matrix adhesion | IEA | biological_process |
| GO:0017022 | Myosin binding | IEA | molecular_function |
| GO:0031032 | Actomyosin structure organization | IEA | biological_process |
| GO:0046777 | Protein autophosphorylation | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0070266 | Necroptotic process | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1293609589 | 0.8027555526 | 0.7305105771 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0634963205 |
| GSE13712_SHEAR | Up | 0.2447898062 |
| GSE13712_STATIC | Up | 0.1247460947 |
| GSE19018 | Down | -0.1125459784 |
| GSE19899_A1 | Up | 0.0842634181 |
| GSE19899_A2 | Down | -0.2179434664 |
| PubMed_21979375_A1 | Down | -0.0152434726 |
| PubMed_21979375_A2 | Up | 0.0556003024 |
| GSE35957 | Up | 0.2615833729 |
| GSE36640 | Up | 0.3280697052 |
| GSE54402 | Down | -0.0238887037 |
| GSE9593 | Up | 0.1725775370 |
| GSE43922 | Down | -0.0215597741 |
| GSE24585 | Down | -0.0052271747 |
| GSE37065 | Up | 0.0712670564 |
| GSE28863_A1 | Up | 0.7048573329 |
| GSE28863_A2 | Up | 1.2112810007 |
| GSE28863_A3 | Down | -0.3653267301 |
| GSE28863_A4 | Up | 0.0471612271 |
| GSE48662 | Down | -0.3475568547 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Phosphoaminophosphonic Acid-Adenylate Ester | DB04395 | EXPT00524 |
| 1,4-Dithiothreitol | DB04447 | EXPT01291 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-9-5p | MIMAT0000441 | MIRT021383 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030789 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047669 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
