HCSGD entry for TRPM4
1. General information
| Official gene symbol | TRPM4 |
|---|---|
| Entrez ID | 54795 |
| Gene full name | transient receptor potential cation channel, subfamily M, member 4 |
| Other gene symbols | PFHB1B TRPM4B |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002407 | Dendritic cell chemotaxis | ISS | biological_process |
| GO:0002724 | Regulation of T cell cytokine production | IDA | biological_process |
| GO:0005216 | Ion channel activity | IEA | molecular_function |
| GO:0005227 | Calcium activated cation channel activity | ISS | molecular_function |
| GO:0005262 | Calcium channel activity | IEA | molecular_function |
| GO:0005516 | Calmodulin binding | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0008284 | Positive regulation of cell proliferation | IDA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016925 | Protein sumoylation | IDA | biological_process |
| GO:0090263 | Positive regulation of canonical Wnt signaling pathway | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2002008510 | 0.5853699252 | 0.8628753846 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1192654777 |
| GSE13712_SHEAR | Up | 0.4766553491 |
| GSE13712_STATIC | Up | 0.7380960030 |
| GSE19018 | Up | 0.3299528173 |
| GSE19899_A1 | Down | -0.4076041457 |
| GSE19899_A2 | Down | -0.3891990028 |
| PubMed_21979375_A1 | Down | -0.3317397418 |
| PubMed_21979375_A2 | Up | 0.1618453640 |
| GSE35957 | Down | -0.2487904791 |
| GSE36640 | Up | 0.4860530148 |
| GSE54402 | Down | -0.1174598610 |
| GSE9593 | Up | 0.4904310952 |
| GSE43922 | Up | 0.0005366097 |
| GSE24585 | Down | -0.0664751981 |
| GSE37065 | Up | 0.0045224479 |
| GSE28863_A1 | Down | -0.0701188787 |
| GSE28863_A2 | Up | 0.0331993136 |
| GSE28863_A3 | Up | 0.1605491269 |
| GSE28863_A4 | Up | 0.0673408036 |
| GSE48662 | Up | 0.3307957145 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017409 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-1 | MIMAT0000416 | MIRT023660 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
