HCSGD entry for LEPROT
1. General information
| Official gene symbol | LEPROT |
|---|---|
| Entrez ID | 54741 |
| Gene full name | leptin receptor overlapping transcript |
| Other gene symbols | LEPR OB-RGRP OBRGRP VPS55 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0005102 | Receptor binding | IDA | molecular_function |
| GO:0005768 | Endosome | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0010008 | Endosome membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0046426 | Negative regulation of JAK-STAT cascade | IDA | biological_process |
| GO:0060400 | Negative regulation of growth hormone receptor signaling pathway | IDA | biological_process |
| GO:2000009 | Negative regulation of protein localization to cell surface | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2384057179 | 0.5312593632 | 0.9242615022 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1042066493 |
| GSE13712_SHEAR | Up | 0.1271644243 |
| GSE13712_STATIC | Up | 0.0513265073 |
| GSE19018 | Down | -0.0563734420 |
| GSE19899_A1 | Down | -0.1301931197 |
| GSE19899_A2 | Up | 0.2888258451 |
| PubMed_21979375_A1 | Up | 0.1838781937 |
| PubMed_21979375_A2 | Up | 0.3357853453 |
| GSE35957 | Up | 0.2464518331 |
| GSE36640 | Up | 1.3078870173 |
| GSE54402 | Down | -0.3830401167 |
| GSE9593 | Up | 0.2563507611 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 0.0476561050 |
| GSE28863_A2 | Up | 0.1808141242 |
| GSE28863_A3 | Down | -0.4324926422 |
| GSE28863_A4 | Down | -0.2608917509 |
| GSE48662 | Up | 0.2367428966 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-340-5p | MIMAT0004692 | MIRT019548 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
