HCSGD entry for PPEF2

1. General information

Official gene symbolPPEF2
Entrez ID5470
Gene full nameprotein phosphatase, EF-hand calcium binding domain 2
Other gene symbolsPPP7CB
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001750Photoreceptor outer segmentIEAcellular_component
GO:0001917Photoreceptor inner segmentIEAcellular_component
GO:0004722Protein serine/threonine phosphatase activityTASmolecular_function
GO:0005506Iron ion bindingIEAmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0006470Protein dephosphorylationTASbiological_process
GO:0007601Visual perceptionIEAbiological_process
GO:0010801Negative regulation of peptidyl-threonine phosphorylationIDAbiological_process
GO:0030145Manganese ion bindingIEAmolecular_function
GO:0030544Hsp70 protein bindingIDAmolecular_function
GO:0031435Mitogen-activated protein kinase kinase kinase bindingIPImolecular_function
GO:0043405Regulation of MAP kinase activityICbiological_process
GO:0043409Negative regulation of MAPK cascadeIDAbiological_process
GO:0043506Regulation of JUN kinase activityICbiological_process
GO:0050906Detection of stimulus involved in sensory perceptionIEAbiological_process
GO:0051879Hsp90 protein bindingIDAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.38388803620.87472655290.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2152512531
GSE13712_SHEARUp0.0407673894
GSE13712_STATICDown-0.2150947274
GSE19018Down-0.0649489365
GSE19899_A1Up0.0138703951
GSE19899_A2Up0.1828912304
PubMed_21979375_A1Down-0.1082054283
PubMed_21979375_A2Up0.1915002947
GSE35957Up0.2137320215
GSE36640Up0.1917600486
GSE54402Up0.0810924285
GSE9593Down-0.1704467110
GSE43922Up0.0383535356
GSE24585Down-0.1559210595
GSE37065Up0.0492740938
GSE28863_A1Up0.0463099646
GSE28863_A2Up0.0686991576
GSE28863_A3Up0.2092005810
GSE28863_A4Up0.0971458743
GSE48662Up0.0070679314

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.