HCSGD entry for LRRN3
1. General information
| Official gene symbol | LRRN3 |
|---|---|
| Entrez ID | 54674 |
| Gene full name | leucine rich repeat neuronal 3 |
| Other gene symbols | FIGLER5 NLRR-3 NLRR3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001934 | Positive regulation of protein phosphorylation | IEA | biological_process |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030131 | Clathrin adaptor complex | IEA | cellular_component |
| GO:0032403 | Protein complex binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0122311918 | 0.0008749022 | 0.2760280206 | 0.0565781863 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 2.9801964065 |
| GSE13712_SHEAR | Down | -0.1897211321 |
| GSE13712_STATIC | Up | 0.1676793634 |
| GSE19018 | Up | 0.8122639545 |
| GSE19899_A1 | Down | -4.6381789157 |
| GSE19899_A2 | Down | -1.5375213296 |
| PubMed_21979375_A1 | Down | -3.9205109241 |
| PubMed_21979375_A2 | Down | -4.6733537559 |
| GSE35957 | Up | 2.4665770432 |
| GSE36640 | Up | 2.2486262991 |
| GSE54402 | Down | -1.4460115222 |
| GSE9593 | Down | -0.4017154510 |
| GSE43922 | Down | -2.5319154804 |
| GSE24585 | Down | -0.0125352884 |
| GSE37065 | Up | 1.8063035638 |
| GSE28863_A1 | Down | -0.2250201632 |
| GSE28863_A2 | Up | 0.2069651325 |
| GSE28863_A3 | Up | 0.2645806335 |
| GSE28863_A4 | Up | 0.0369275568 |
| GSE48662 | Down | -1.1313076995 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-181a-5p | MIMAT0000256 | MIRT025063 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
