HCSGD entry for PPA1
1. General information
| Official gene symbol | PPA1 |
|---|---|
| Entrez ID | 5464 |
| Gene full name | pyrophosphatase (inorganic) 1 |
| Other gene symbols | IOPPP PP PP1 SID6-8061 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | IEA | molecular_function |
| GO:0004427 | Inorganic diphosphatase activity | EXP IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006418 | TRNA aminoacylation for protein translation | TAS | biological_process |
| GO:0006796 | Phosphate-containing compound metabolic process | IEA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0071344 | Diphosphate metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7326248433 | 0.1159272520 | 0.9999902473 | 0.6526890267 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1511036899 |
| GSE13712_SHEAR | Down | -0.0495794448 |
| GSE13712_STATIC | Up | 0.2161657922 |
| GSE19018 | Down | -0.0309561592 |
| GSE19899_A1 | Down | -0.2246953227 |
| GSE19899_A2 | Up | 0.3366901984 |
| PubMed_21979375_A1 | Down | -0.2210031234 |
| PubMed_21979375_A2 | Up | 0.2443254583 |
| GSE35957 | Down | -0.4785259227 |
| GSE36640 | Up | 0.2848532587 |
| GSE54402 | Down | -0.4680374822 |
| GSE9593 | Up | 0.0334906057 |
| GSE43922 | Down | -0.0095120999 |
| GSE24585 | Down | -0.8332042084 |
| GSE37065 | Up | 0.2581737776 |
| GSE28863_A1 | Down | -0.0654787886 |
| GSE28863_A2 | Down | -0.0872669693 |
| GSE28863_A3 | Down | -0.2104160949 |
| GSE28863_A4 | Up | 0.1544102784 |
| GSE48662 | Down | -0.5684405090 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028424 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031461 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-361-5p | MIMAT0000703 | MIRT044072 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
