HCSGD entry for FBXL19


1. General information

Official gene symbolFBXL19
Entrez ID54620
Gene full nameF-box and leucine-rich repeat protein 19
Other gene symbolsFbl19 JHDM1C
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEAmolecular_function
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0019005SCF ubiquitin ligase complexIDAcellular_component
GO:0043161Proteasome-mediated ubiquitin-dependent protein catabolic processIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.47410981350.40152607420.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0581608350
GSE13712_SHEARUp0.0449209265
GSE13712_STATICUp0.0543662120
GSE19018Down-0.0490683956
GSE19899_A1Up0.0251245575
GSE19899_A2Up1.0379894258
PubMed_21979375_A1Down-0.2848111132
PubMed_21979375_A2Up0.0433964847
GSE35957Down-0.1607566061
GSE36640Down-0.2226453155
GSE54402Up0.4175058424
GSE9593Down-0.3990792187
GSE43922Up0.0797946825
GSE24585Down-0.4617094105
GSE37065Down-0.0067735733
GSE28863_A1Down-0.1892590353
GSE28863_A2Down-0.2154751677
GSE28863_A3Up0.0233411240
GSE28863_A4Up0.0961712471
GSE48662Up0.2397232042

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-744-5pMIMAT0004945MIRT037597CLASHFunctional MTI (Weak)23622248
hsa-miR-615-3pMIMAT0003283MIRT040201CLASHFunctional MTI (Weak)23622248
hsa-miR-193b-3pMIMAT0002819MIRT041349CLASHFunctional MTI (Weak)23622248
hsa-miR-423-3pMIMAT0001340MIRT042632CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049576CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.