HCSGD entry for UGT1A8

1. General information

Official gene symbolUGT1A8
Entrez ID54576
Gene full nameUDP glucuronosyltransferase 1 family, polypeptide A8
Other gene symbolsUDPGT UDPGT 1-8 UGT-1H UGT1-08 UGT1.8 UGT1A8S UGT1H
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001972Retinoic acid bindingICmolecular_function
GO:0004857Enzyme inhibitor activityIDAmolecular_function
GO:0005496Steroid bindingIDAmolecular_function
GO:0005504Fatty acid bindingIDAmolecular_function
GO:0005789Endoplasmic reticulum membraneIEAcellular_component
GO:0006631Fatty acid metabolic processIC IDAbiological_process
GO:0008144Drug bindingICmolecular_function
GO:0008202Steroid metabolic processICbiological_process
GO:0009804Coumarin metabolic processICbiological_process
GO:0015020Glucuronosyltransferase activityIDAmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0017144Drug metabolic processIDAbiological_process
GO:0019899Enzyme bindingICmolecular_function
GO:0031324Negative regulation of cellular metabolic processIDAbiological_process
GO:0042573Retinoic acid metabolic processICbiological_process
GO:0042803Protein homodimerization activityIPImolecular_function
GO:0043086Negative regulation of catalytic activityIDAbiological_process
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0045922Negative regulation of fatty acid metabolic processICbiological_process
GO:0045939Negative regulation of steroid metabolic processICbiological_process
GO:0046982Protein heterodimerization activityIPImolecular_function
GO:0050790Regulation of catalytic activityIDAbiological_process
GO:0051552Flavone metabolic processIDAbiological_process
GO:0052696Flavonoid glucuronidationIDAbiological_process
GO:0052697Xenobiotic glucuronidationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.51624398770.97614763880.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.3235597192

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.