HCSGD entry for POU4F1

1. General information

Official gene symbolPOU4F1
Entrez ID5457
Gene full namePOU class 4 homeobox 1
Other gene symbolsBRN3A Oct-T1 RDC-1 brn-3A
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterISSbiological_process
GO:0000790Nuclear chromatinIEAcellular_component
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA bindingISSmolecular_function
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptionIEAmolecular_function
GO:0001967Suckling behaviorIEAbiological_process
GO:0003223Ventricular compact myocardium morphogenesisIEAbiological_process
GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activityISSmolecular_function
GO:0006366Transcription from RNA polymerase II promoterISSbiological_process
GO:0007409AxonogenesisTASbiological_process
GO:0007416Synapse assemblyTASbiological_process
GO:0007498Mesoderm developmentIEAbiological_process
GO:0021535Cell migration in hindbrainIEAbiological_process
GO:0021559Trigeminal nerve developmentISSbiological_process
GO:0021953Central nervous system neuron differentiationIEAbiological_process
GO:0021986Habenula developmentIEAbiological_process
GO:0043005Neuron projectionIEAcellular_component
GO:0043065Positive regulation of apoptotic processIEAbiological_process
GO:0043524Negative regulation of neuron apoptotic processTASbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterISSbiological_process
GO:0048665Neuron fate specificationISSbiological_process
GO:0048880Sensory system developmentISSbiological_process
GO:0048935Peripheral nervous system neuron developmentISSbiological_process
GO:0050767Regulation of neurogenesisIEAbiological_process
GO:0051355Proprioception involved in equilibrioceptionIEAbiological_process
GO:0060384InnervationTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.49666008130.59092923520.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0746192375
GSE13712_SHEARDown-0.7364958992
GSE13712_STATICDown-0.1832655494
GSE19018Up0.1544041058
GSE19899_A1Up0.1888837988
GSE19899_A2Up0.0418545012
PubMed_21979375_A1Down-0.3219935172
PubMed_21979375_A2Down-0.1240671794
GSE35957Up0.0773932947
GSE36640Up0.0490104671
GSE54402Up0.1413896286
GSE9593Down-0.0385322729
GSE43922Up0.0621194056
GSE24585Up0.2059292372
GSE37065Down-0.0687105974
GSE28863_A1Up0.1414118889
GSE28863_A2Down-0.0151184395
GSE28863_A3Up0.2533524628
GSE28863_A4Up0.0308940253
GSE48662Up0.0942815837

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT030102MicroarrayFunctional MTI (Weak)19088304
hsa-miR-30b-5pMIMAT0000420MIRT046165CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.