HCSGD entry for POU3F3

1. General information

Official gene symbolPOU3F3
Entrez ID5455
Gene full namePOU class 3 homeobox 3
Other gene symbolsBRN1 OTF8
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusISScellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007417Central nervous system developmentTASbiological_process
GO:0008284Positive regulation of cell proliferationISSbiological_process
GO:0010628Positive regulation of gene expressionISSbiological_process
GO:0021799Cerebral cortex radially oriented cell migrationIEAbiological_process
GO:0021869Forebrain ventricular zone progenitor cell divisionIEAbiological_process
GO:0043066Negative regulation of apoptotic processISSbiological_process
GO:0043565Sequence-specific DNA bindingISSmolecular_function
GO:0045892Negative regulation of transcription, DNA-templatedISSbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedISSbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0071837HMG box domain bindingIEAmolecular_function
GO:0072218Metanephric ascending thin limb developmentISSbiological_process
GO:0072227Metanephric macula densa developmentISSbiological_process
GO:0072233Metanephric thick ascending limb developmentISSbiological_process
GO:0072236Metanephric loop of Henle developmentISSbiological_process
GO:0072240Metanephric DCT cell differentiationISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.16581378370.70440021660.80571234321.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0322161634
GSE13712_SHEARDown-0.0227597196
GSE13712_STATICDown-0.0080975816
GSE19018Up0.1232187137
GSE19899_A1Up0.0856734092
GSE19899_A2Up0.0850573915
PubMed_21979375_A1Up0.1743640063
PubMed_21979375_A2Down-0.0456370834
GSE35957Up0.5675452729
GSE36640Up0.0706841290
GSE54402Up0.0346469485
GSE9593Down-0.1076643627
GSE43922Up0.0235840513
GSE24585Down-0.0939937813
GSE37065Down-0.2555628096
GSE28863_A1Up0.4322196361
GSE28863_A2Up0.0657643518
GSE28863_A3Up0.8496649315
GSE28863_A4Up0.0691068997
GSE48662Down-0.0515231707

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.