HCSGD entry for USP53
1. General information
| Official gene symbol | USP53 |
|---|---|
| Entrez ID | 54532 |
| Gene full name | ubiquitin specific peptidase 53 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004221 | Ubiquitin thiolesterase activity | IDA IEA | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | IEA | biological_process |
| GO:0008150 | Biological_process | ND | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0001932525 | 0.5976997151 | 0.0400519685 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.9248792066 |
| GSE13712_SHEAR | Up | 1.1541488860 |
| GSE13712_STATIC | Up | 0.5002779814 |
| GSE19018 | Down | -0.1689299212 |
| GSE19899_A1 | Up | 0.7749021453 |
| GSE19899_A2 | Up | 1.7664747364 |
| PubMed_21979375_A1 | Up | 2.0878648873 |
| PubMed_21979375_A2 | Up | 2.2264253368 |
| GSE35957 | Up | 1.7435137550 |
| GSE36640 | Up | 1.6306237089 |
| GSE54402 | Up | 0.4605107961 |
| GSE9593 | Up | 0.9271021786 |
| GSE43922 | Up | 1.2851803342 |
| GSE24585 | Up | 0.8031250689 |
| GSE37065 | Down | -0.0317189603 |
| GSE28863_A1 | Down | -0.1783972484 |
| GSE28863_A2 | Up | 1.1004863694 |
| GSE28863_A3 | Down | -0.9217656639 |
| GSE28863_A4 | Down | -0.3938931996 |
| GSE48662 | Down | -0.1052184844 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30b-5p | MIMAT0000420 | MIRT023405 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT032060 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
