HCSGD entry for POU2F2

1. General information

Official gene symbolPOU2F2
Entrez ID5452
Gene full namePOU class 2 homeobox 2
Other gene symbolsOCT2 OTF2 Oct-2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002335Mature B cell differentiationIEAbiological_process
GO:0002380Immunoglobulin secretion involved in immune responseIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0006959Humoral immune responseTASbiological_process
GO:0019904Protein domain specific bindingIEAmolecular_function
GO:0043565Sequence-specific DNA bindingIDA IEAmolecular_function
GO:0045893Positive regulation of transcription, DNA-templatedIEAbiological_process
GO:0048469Cell maturationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00156346640.97768389120.10606185571.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.4787737161
GSE13712_SHEARUp0.0522697389
GSE13712_STATICDown-0.0043753635
GSE19018Up0.0664015952
GSE19899_A1Up1.3357041345
GSE19899_A2Up3.4651925023
PubMed_21979375_A1Up2.0201452089
PubMed_21979375_A2Up2.3955112021
GSE35957Up0.0671947194
GSE36640Up0.4759221908
GSE54402Up1.6905588479
GSE9593Up0.0470552847
GSE43922Up0.9328358763
GSE24585Down-0.1285438446
GSE37065Up0.4952603388
GSE28863_A1Down-0.3968116430
GSE28863_A2Down-0.2078602367
GSE28863_A3Up0.3464570735
GSE28863_A4Up0.0628165363
GSE48662Down-0.0122277344

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-9-5pMIMAT0000441MIRT000639Luciferase reporter assayNon-Functional MTI19956200
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.