HCSGD entry for HMGCLL1
1. General information
| Official gene symbol | HMGCLL1 |
|---|---|
| Entrez ID | 54511 |
| Gene full name | 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 |
| Other gene symbols | bA418P12.1 er-cHL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004419 | Hydroxymethylglutaryl-CoA lyase activity | IDA IEA ISS | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0016020 | Membrane | IDA | cellular_component |
| GO:0046872 | Metal ion binding | ISS TAS | molecular_function |
| GO:0046951 | Ketone body biosynthetic process | IDA | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4097005471 | 0.7595400935 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0019545235 |
| GSE13712_SHEAR | Up | 0.0723766148 |
| GSE13712_STATIC | Up | 0.0089550025 |
| GSE19018 | Down | -0.0078865626 |
| GSE19899_A1 | Down | -0.0629755351 |
| GSE19899_A2 | Down | -0.0269709754 |
| PubMed_21979375_A1 | Down | -0.0466029045 |
| PubMed_21979375_A2 | Down | -0.0522368249 |
| GSE35957 | Up | 0.2027525621 |
| GSE36640 | Down | -0.0126436611 |
| GSE54402 | Down | -0.2788869892 |
| GSE9593 | Down | -0.0561344000 |
| GSE43922 | Down | -0.0112357643 |
| GSE24585 | Up | 1.6402541000 |
| GSE37065 | Up | 0.0140947317 |
| GSE28863_A1 | Up | 0.0386561011 |
| GSE28863_A2 | Up | 0.0539944411 |
| GSE28863_A3 | Up | 0.1530618318 |
| GSE28863_A4 | Up | 0.0163079699 |
| GSE48662 | Up | 0.0221628743 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT019060 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
