HCSGD entry for TMX3
1. General information
| Official gene symbol | TMX3 |
|---|---|
| Entrez ID | 54495 |
| Gene full name | thioredoxin-related transmembrane protein 3 |
| Other gene symbols | PDIA13 TXNDC10 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003756 | Protein disulfide isomerase activity | IEA | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0006662 | Glycerol ether metabolic process | IEA | biological_process |
| GO:0009986 | Cell surface | IDA | cellular_component |
| GO:0015035 | Protein disulfide oxidoreductase activity | IEA | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016853 | Isomerase activity | IEA | molecular_function |
| GO:0045454 | Cell redox homeostasis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9208617530 | 0.1364737738 | 0.9999902473 | 0.7117349316 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1689736894 |
| GSE13712_SHEAR | Down | -0.1429668502 |
| GSE13712_STATIC | Up | 0.1437828526 |
| GSE19018 | Down | -0.0410008712 |
| GSE19899_A1 | Down | -0.0363327011 |
| GSE19899_A2 | Up | 0.2609890091 |
| PubMed_21979375_A1 | Down | -0.7872331273 |
| PubMed_21979375_A2 | Down | -0.1706066669 |
| GSE35957 | Down | -0.1408021035 |
| GSE36640 | Up | 0.1408889428 |
| GSE54402 | Down | -0.2198975437 |
| GSE9593 | Down | -0.3969617152 |
| GSE43922 | Down | -0.0639660539 |
| GSE24585 | Down | -0.3628849009 |
| GSE37065 | Down | -0.1455954009 |
| GSE28863_A1 | Up | 0.1599205720 |
| GSE28863_A2 | Down | -0.0497344664 |
| GSE28863_A3 | Down | -0.2486079150 |
| GSE28863_A4 | Up | 0.2094917407 |
| GSE48662 | Up | 0.1507024699 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-590-3p | MIMAT0004801 | MIRT016223 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-375 | MIMAT0000728 | MIRT020010 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020633 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT027953 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-877-5p | MIMAT0004949 | MIRT037341 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-2-3p | MIMAT0004550 | MIRT038695 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
