HCSGD entry for PLEKHA5
1. General information
| Official gene symbol | PLEKHA5 |
|---|---|
| Entrez ID | 54477 |
| Gene full name | pleckstrin homology domain containing, family A member 5 |
| Other gene symbols | PEPP-2 PEPP2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005545 | 1-phosphatidylinositol binding | NAS | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0008150 | Biological_process | ND | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3379596900 | 0.3638338475 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0419277562 |
| GSE13712_SHEAR | Down | -0.2619023443 |
| GSE13712_STATIC | Up | 0.0372558917 |
| GSE19018 | Up | 0.0308086866 |
| GSE19899_A1 | Up | 0.2542477275 |
| GSE19899_A2 | Up | 0.0433092285 |
| PubMed_21979375_A1 | Up | 0.5486291374 |
| PubMed_21979375_A2 | Up | 0.5354781099 |
| GSE35957 | Down | -0.5132131994 |
| GSE36640 | Down | -0.3093704457 |
| GSE54402 | Down | -0.2468210200 |
| GSE9593 | Down | -0.2959573055 |
| GSE43922 | Up | 0.2176062495 |
| GSE24585 | Down | -0.0380151715 |
| GSE37065 | Up | 0.0009176437 |
| GSE28863_A1 | Up | 0.6761199690 |
| GSE28863_A2 | Up | 0.4751005736 |
| GSE28863_A3 | Down | -0.5178804225 |
| GSE28863_A4 | Down | -0.1118797594 |
| GSE48662 | Down | -0.0623092413 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020804 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050272 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
