HCSGD entry for RNF216
1. General information
| Official gene symbol | RNF216 |
|---|---|
| Entrez ID | 54476 |
| Gene full name | ring finger protein 216 |
| Other gene symbols | TRIAD3 U7I1 UBCE7IP1 ZIN |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0016874 | Ligase activity | IEA | molecular_function |
| GO:0032648 | Regulation of interferon-beta production | IDA | biological_process |
| GO:0043161 | Proteasome-mediated ubiquitin-dependent protein catabolic process | IDA | biological_process |
| GO:0050691 | Regulation of defense response to virus by host | IDA | biological_process |
| GO:0070936 | Protein K48-linked ubiquitination | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7047066981 | 0.4209177881 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2293838816 |
| GSE13712_SHEAR | Up | 0.1049730649 |
| GSE13712_STATIC | Down | -0.0085978941 |
| GSE19018 | Down | -0.1203594538 |
| GSE19899_A1 | Down | -0.2647028067 |
| GSE19899_A2 | Up | 0.0853955994 |
| PubMed_21979375_A1 | Down | -0.0978259288 |
| PubMed_21979375_A2 | Down | -0.0470169552 |
| GSE35957 | Up | 0.0436476967 |
| GSE36640 | Up | 0.1800948274 |
| GSE54402 | Down | -0.1632381887 |
| GSE9593 | Down | -0.0000870905 |
| GSE43922 | Up | 0.0060185072 |
| GSE24585 | Down | -0.1640819816 |
| GSE37065 | Down | -0.0078702129 |
| GSE28863_A1 | Up | 0.3427822478 |
| GSE28863_A2 | Up | 0.3493981575 |
| GSE28863_A3 | Down | -0.3185760399 |
| GSE28863_A4 | Up | 0.0909311239 |
| GSE48662 | Up | 0.2050609532 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-455-3p | MIMAT0004784 | MIRT037895 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044679 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
