HCSGD entry for RIN2
1. General information
| Official gene symbol | RIN2 |
|---|---|
| Entrez ID | 54453 |
| Gene full name | Ras and Rab interactor 2 |
| Other gene symbols | MACS RASSF4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005083 | Small GTPase regulator activity | NAS | molecular_function |
| GO:0005096 | GTPase activator activity | IEA | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006897 | Endocytosis | IEA | biological_process |
| GO:0007165 | Signal transduction | IEA | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | NAS | biological_process |
| GO:0017112 | Rab guanyl-nucleotide exchange factor activity | NAS | molecular_function |
| GO:0032313 | Regulation of Rab GTPase activity | NAS | biological_process |
| GO:0032318 | Regulation of Ras GTPase activity | NAS | biological_process |
| GO:0043087 | Regulation of GTPase activity | NAS | biological_process |
| GO:0050790 | Regulation of catalytic activity | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6329276395 | 0.1360092056 | 0.9999902473 | 0.7112851778 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2567442064 |
| GSE13712_SHEAR | Up | 0.1809275917 |
| GSE13712_STATIC | Down | -0.2240502936 |
| GSE19018 | Up | 0.2889173173 |
| GSE19899_A1 | Down | -0.6128614494 |
| GSE19899_A2 | Down | -0.5013045071 |
| PubMed_21979375_A1 | Down | -0.9938818577 |
| PubMed_21979375_A2 | Down | -0.2339048028 |
| GSE35957 | Up | 0.1756160427 |
| GSE36640 | Up | 0.2533698723 |
| GSE54402 | Down | -0.1261132739 |
| GSE9593 | Down | -0.2433349673 |
| GSE43922 | Down | -0.2185641775 |
| GSE24585 | Up | 0.3997547325 |
| GSE37065 | Up | 0.0891467372 |
| GSE28863_A1 | Up | 0.1983625834 |
| GSE28863_A2 | Down | -0.1388452034 |
| GSE28863_A3 | Down | -0.0079999180 |
| GSE28863_A4 | Up | 0.0719249187 |
| GSE48662 | Down | -0.3952939591 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-429 | MIMAT0001536 | MIRT016643 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-200a-3p | MIMAT0000682 | MIRT020353 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-200c-3p | MIMAT0000617 | MIRT021076 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-141-3p | MIMAT0000432 | MIRT021656 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-200b-3p | MIMAT0000318 | MIRT024130 | Reporter assay | Functional MTI | 20005803 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
