HCSGD entry for POLRMT
1. General information
| Official gene symbol | POLRMT |
|---|---|
| Entrez ID | 5442 |
| Gene full name | polymerase (RNA) mitochondrial (DNA directed) |
| Other gene symbols | APOLMT MTRNAP MTRPOL h-mtRPOL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003899 | DNA-directed RNA polymerase activity | IDA IEA TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006390 | Transcription from mitochondrial promoter | IDA TAS | biological_process |
| GO:0006391 | Transcription initiation from mitochondrial promoter | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0042645 | Mitochondrial nucleoid | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0494701341 | 0.6137745070 | 0.4882649813 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0703151382 |
| GSE13712_SHEAR | Up | 0.1224514762 |
| GSE13712_STATIC | Up | 0.0875766205 |
| GSE19018 | Up | 0.0931434001 |
| GSE19899_A1 | Up | 0.2872498179 |
| GSE19899_A2 | Up | 0.6285016620 |
| PubMed_21979375_A1 | Up | 1.2714790723 |
| PubMed_21979375_A2 | Up | 1.2405707367 |
| GSE35957 | Down | -0.1889782595 |
| GSE36640 | Up | 0.1714566702 |
| GSE54402 | Up | 0.2498291184 |
| GSE9593 | Down | -0.0883116933 |
| GSE43922 | Up | 0.6160197885 |
| GSE24585 | Down | -0.7449993035 |
| GSE37065 | Down | -0.1666266813 |
| GSE28863_A1 | Down | -0.3911828236 |
| GSE28863_A2 | Down | -0.4382916797 |
| GSE28863_A3 | Up | 0.3429600987 |
| GSE28863_A4 | Up | 0.0785565776 |
| GSE48662 | Up | 0.2246222602 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT024018 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-30e-5p | MIMAT0000692 | MIRT044146 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30b-5p | MIMAT0000420 | MIRT046122 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049050 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
