HCSGD entry for POLR2G

1. General information

Official gene symbolPOLR2G
Entrez ID5436
Gene full namepolymerase (RNA) II (DNA directed) polypeptide G
Other gene symbolsRPB19 RPB7 hRPB19 hsRPB7
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000398MRNA splicing, via spliceosomeTASbiological_process
GO:0003723RNA bindingIEAmolecular_function
GO:0003899DNA-directed RNA polymerase activityIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005665DNA-directed RNA polymerase II, core complexIDAcellular_component
GO:0006281DNA repairTASbiological_process
GO:0006283Transcription-coupled nucleotide-excision repairTASbiological_process
GO:0006289Nucleotide-excision repairTASbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006366Transcription from RNA polymerase II promoterIDA TASbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterTASbiological_process
GO:0006368Transcription elongation from RNA polymerase II promoterTASbiological_process
GO:00063707-methylguanosine mRNA cappingTASbiological_process
GO:0006915Apoptotic processIEAbiological_process
GO:0008380RNA splicingTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0050434Positive regulation of viral transcriptionTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.99241309600.02973408310.99999024730.3260961667

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0222699836
GSE13712_SHEARDown-0.5947103468
GSE13712_STATICDown-0.3120025404
GSE19018Down-0.3106332367
GSE19899_A1Down-0.2871476225
GSE19899_A2Down-0.6816130602
PubMed_21979375_A1Down-0.1356996668
PubMed_21979375_A2Down-0.3923305920
GSE35957Down-0.2144777604
GSE36640Down-0.5397870931
GSE54402Down-0.1158575865
GSE9593Down-0.3864534886
GSE43922Down-0.2158298206
GSE24585Down-0.0392991601
GSE37065Down-0.1602893800
GSE28863_A1Up0.0511645299
GSE28863_A2Up0.0254517153
GSE28863_A3Down-0.2646399448
GSE28863_A4Up0.1023969561
GSE48662Down-0.0223312887

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT028902MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.