HCSGD entry for POLD2

1. General information

Official gene symbolPOLD2
Entrez ID5425
Gene full namepolymerase (DNA directed), delta 2, accessory subunit
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000278Mitotic cell cycleTASbiological_process
GO:0000722Telomere maintenance via recombinationTASbiological_process
GO:0000723Telomere maintenanceTASbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0003887DNA-directed DNA polymerase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006260DNA replicationTASbiological_process
GO:0006271DNA strand elongation involved in DNA replicationTASbiological_process
GO:0006281DNA repairTASbiological_process
GO:0006283Transcription-coupled nucleotide-excision repairTASbiological_process
GO:0006284Base-excision repairTASbiological_process
GO:0006289Nucleotide-excision repairTASbiological_process
GO:0006297Nucleotide-excision repair, DNA gap fillingTASbiological_process
GO:0032201Telomere maintenance via semi-conservative replicationTASbiological_process
GO:0043625Delta DNA polymerase complexIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.60592331600.03477667640.99999024730.3527386898

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0361310115
GSE13712_SHEARDown-0.2065152878
GSE13712_STATICDown-0.2500661634
GSE19018Up0.5002280178
GSE19899_A1Down-0.7549932298
GSE19899_A2Down-0.0919484153
PubMed_21979375_A1Up0.8116212807
PubMed_21979375_A2Down-0.4417376990
GSE35957Down-0.2490329336
GSE36640Down-1.3265082349
GSE54402Up0.6232701278
GSE9593Down-0.3933168123
GSE43922Down-0.3829362935
GSE24585Down-0.5862487133
GSE37065Down-0.2252414022
GSE28863_A1Down-0.2648171380
GSE28863_A2Up0.0705369233
GSE28863_A3Up0.1410568852
GSE28863_A4Up0.0060087860
GSE48662Up0.3215706426

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-let-7b-5pMIMAT0000063MIRT001608pSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
hsa-miR-222-3pMIMAT0000279MIRT046820CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.