HCSGD entry for NANS
1. General information
| Official gene symbol | NANS |
|---|---|
| Entrez ID | 54187 |
| Gene full name | N-acetylneuraminic acid synthase |
| Other gene symbols | SAS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0005737 | Cytoplasm | NAS | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0008781 | N-acylneuraminate cytidylyltransferase activity | NAS | molecular_function |
| GO:0009103 | Lipopolysaccharide biosynthetic process | NAS | biological_process |
| GO:0016051 | Carbohydrate biosynthetic process | IEA | biological_process |
| GO:0047444 | N-acylneuraminate-9-phosphate synthase activity | IEA | molecular_function |
| GO:0050462 | N-acetylneuraminate synthase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9399040538 | 0.0909825387 | 0.9999902473 | 0.5735482643 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0367451688 |
| GSE13712_SHEAR | Down | -0.0675564392 |
| GSE13712_STATIC | Down | -0.1646404289 |
| GSE19018 | Down | -0.0096894224 |
| GSE19899_A1 | Down | -0.2356153554 |
| GSE19899_A2 | Up | 0.1046511153 |
| PubMed_21979375_A1 | Down | -0.0590228452 |
| PubMed_21979375_A2 | Down | -0.3915467580 |
| GSE35957 | Down | -0.3295886769 |
| GSE36640 | Down | -0.2850172053 |
| GSE54402 | Down | -0.0508129423 |
| GSE9593 | Down | -0.1904829362 |
| GSE43922 | Down | -0.2254087153 |
| GSE24585 | Up | 0.6205598515 |
| GSE37065 | Down | -0.3010286463 |
| GSE28863_A1 | Down | -0.1377055477 |
| GSE28863_A2 | Down | -0.1905130354 |
| GSE28863_A3 | Down | -0.1823196143 |
| GSE28863_A4 | Up | 0.2018339044 |
| GSE48662 | Down | -0.4486424520 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-324-5p | MIMAT0000761 | MIRT043076 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
