HCSGD entry for PMS2
1. General information
| Official gene symbol | PMS2 |
|---|---|
| Entrez ID | 5395 |
| Gene full name | PMS2 postmeiotic segregation increased 2 (S. cerevisiae) |
| Other gene symbols | HNPCC4 PMS2CL PMSL2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0003697 | Single-stranded DNA binding | IDA | molecular_function |
| GO:0004519 | Endonuclease activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IC | cellular_component |
| GO:0006200 | ATP catabolic process | IBA | biological_process |
| GO:0006298 | Mismatch repair | IDA IEA | biological_process |
| GO:0007131 | Reciprocal meiotic recombination | IBA | biological_process |
| GO:0016446 | Somatic hypermutation of immunoglobulin genes | IBA | biological_process |
| GO:0016447 | Somatic recombination of immunoglobulin gene segments | IEA | biological_process |
| GO:0016887 | ATPase activity | IBA | molecular_function |
| GO:0030983 | Mismatched DNA binding | IEA | molecular_function |
| GO:0032138 | Single base insertion or deletion binding | IDA | molecular_function |
| GO:0032300 | Mismatch repair complex | IBA | cellular_component |
| GO:0032389 | MutLalpha complex | IBA | cellular_component |
| GO:0032407 | MutSalpha complex binding | IDA | molecular_function |
| GO:0042493 | Response to drug | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8620171840 | 0.7925842179 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | - | - |
| GSE13712_SHEAR | - | - |
| GSE13712_STATIC | - | - |
| GSE19018 | - | - |
| GSE19899_A1 | - | - |
| GSE19899_A2 | - | - |
| PubMed_21979375_A1 | - | - |
| PubMed_21979375_A2 | - | - |
| GSE35957 | - | - |
| GSE36640 | - | - |
| GSE54402 | - | - |
| GSE9593 | - | - |
| GSE43922 | Down | -0.1553016021 |
| GSE24585 | Up | 0.2294191749 |
| GSE37065 | Down | -0.0526658377 |
| GSE28863_A1 | Down | -0.1134290216 |
| GSE28863_A2 | Up | 0.1688724518 |
| GSE28863_A3 | Up | 0.0172724585 |
| GSE28863_A4 | Down | -0.0073354679 |
| GSE48662 | Up | 0.0206342353 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Phosphothiophosphoric Acid-Adenylate Ester | DB02930 | EXPT00458 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-324-5p | MIMAT0000761 | MIRT043223 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-96-5p | MIMAT0000095 | MIRT048727 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
