HCSGD entry for DUOX1

1. General information

Official gene symbolDUOX1
Entrez ID53905
Gene full namedual oxidase 1
Other gene symbolsLNOX1 NOXEF1 THOX1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004601Peroxidase activityIEAmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005886Plasma membraneIEAcellular_component
GO:0006590Thyroid hormone generationIEAbiological_process
GO:0006979Response to oxidative stressIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016174NAD(P)H oxidase activityNASmolecular_function
GO:0016324Apical plasma membraneNAScellular_component
GO:0019221Cytokine-mediated signaling pathwayIDAbiological_process
GO:0020037Heme bindingIEAmolecular_function
GO:0042335Cuticle developmentIMPbiological_process
GO:0042446Hormone biosynthetic processIEAbiological_process
GO:0042554Superoxide anion generationNASbiological_process
GO:0042744Hydrogen peroxide catabolic processIEAbiological_process
GO:0050661NADP bindingNASmolecular_function
GO:0050665Hydrogen peroxide biosynthetic processNASbiological_process
GO:0051591Response to cAMPIDA ISSbiological_process
GO:0055114Oxidation-reduction processTASbiological_process
GO:0072593Reactive oxygen species metabolic processIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.48627690820.92274573150.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0058204800
GSE13712_SHEARUp0.0282852910
GSE13712_STATICUp0.0194806745
GSE19018Up0.0829618621
GSE19899_A1Up0.1178252105
GSE19899_A2Up0.0486584464
PubMed_21979375_A1Down-0.0845553232
PubMed_21979375_A2Up0.1087949007
GSE35957Up0.1578537739
GSE36640Up0.0893087232
GSE54402Down-0.0069415339
GSE9593Down-0.0494919334
GSE43922Up0.0111820484
GSE24585Up0.0360483345
GSE37065Up0.2998859366
GSE28863_A1Down-0.0188547154
GSE28863_A2Down-0.0683059665
GSE28863_A3Up0.2499479461
GSE28863_A4Up0.0868185772
GSE48662Up0.1615508088

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.