HCSGD entry for PMS1
1. General information
| Official gene symbol | PMS1 |
|---|---|
| Entrez ID | 5378 |
| Gene full name | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) |
| Other gene symbols | HNPCC3 PMSL1 hPMS1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | TAS | molecular_function |
| GO:0003697 | Single-stranded DNA binding | IBA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | TAS | cellular_component |
| GO:0006200 | ATP catabolic process | IBA | biological_process |
| GO:0006298 | Mismatch repair | IBA IEA | biological_process |
| GO:0007131 | Reciprocal meiotic recombination | IBA | biological_process |
| GO:0016887 | ATPase activity | IBA | molecular_function |
| GO:0030983 | Mismatched DNA binding | IEA | molecular_function |
| GO:0032300 | Mismatch repair complex | IBA | cellular_component |
| GO:0032389 | MutLalpha complex | IBA | cellular_component |
| GO:0032407 | MutSalpha complex binding | IBA | molecular_function |
| GO:0042493 | Response to drug | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7500163482 | 0.3538267277 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1024612305 |
| GSE13712_SHEAR | Up | 0.1316266426 |
| GSE13712_STATIC | Up | 0.2716988157 |
| GSE19018 | Up | 0.1217621082 |
| GSE19899_A1 | Up | 0.0497474045 |
| GSE19899_A2 | Up | 0.3790276755 |
| PubMed_21979375_A1 | Up | 0.0239582954 |
| PubMed_21979375_A2 | Down | -0.1800015089 |
| GSE35957 | Up | 0.0379858235 |
| GSE36640 | Down | -0.4370543488 |
| GSE54402 | Down | -0.2232523431 |
| GSE9593 | Up | 0.0691970987 |
| GSE43922 | Down | -0.0810425825 |
| GSE24585 | Down | -0.1706595541 |
| GSE37065 | Down | -0.1556659141 |
| GSE28863_A1 | Down | -0.1181613748 |
| GSE28863_A2 | Up | 0.2396934478 |
| GSE28863_A3 | Down | -0.2987272095 |
| GSE28863_A4 | Down | -0.1381646431 |
| GSE48662 | Down | -0.0124581473 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT000891 | Microarray | Functional MTI (Weak) | 18362358 |
| hsa-miR-15a-5p | MIMAT0000068 | MIRT000892 | Microarray | Functional MTI (Weak) | 18362358 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-15a-5p | MIMAT0000068 | NA | hsa-miR-15a | 18362358 | |||
| hsa-miR-16-5p | MIMAT0000069 | NA | hsa-miR-16 | 18362358 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
