HCSGD entry for PMM2


1. General information

Official gene symbolPMM2
Entrez ID5373
Gene full namephosphomannomutase 2
Other gene symbolsCDG1 CDG1a CDGS PMI PMI1 PMM 2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004615Phosphomannomutase activityIEAmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006486Protein glycosylationTASbiological_process
GO:0006488Dolichol-linked oligosaccharide biosynthetic processTASbiological_process
GO:0009298GDP-mannose biosynthetic processIEA TASbiological_process
GO:0018279Protein N-linked glycosylation via asparagineTASbiological_process
GO:0019307Mannose biosynthetic processIEAbiological_process
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0043687Post-translational protein modificationTASbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.38853407930.04457726150.99999024730.3973308838

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1929444705
GSE13712_SHEARDown-0.2486843639
GSE13712_STATICUp0.2261142503
GSE19018Down-0.4059634120
GSE19899_A1Down-0.3109408453
GSE19899_A2Up0.6798274140
PubMed_21979375_A1Up1.4358429094
PubMed_21979375_A2Up1.1164675194
GSE35957Down-0.0236431415
GSE36640Down-0.3718875299
GSE54402Up0.3324696598
GSE9593Up0.0839978893
GSE43922Up0.0147881486
GSE24585Down-0.8475064798
GSE37065Down-0.2108657591
GSE28863_A1Down-0.4163999572
GSE28863_A2Down-0.2740417129
GSE28863_A3Down-0.2768059995
GSE28863_A4Up0.1362174174
GSE48662Down-0.4171171762

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-484MIMAT0002174MIRT042073CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.