HCSGD entry for PLRG1
1. General information
| Official gene symbol | PLRG1 |
|---|---|
| Entrez ID | 5356 |
| Gene full name | pleiotropic regulator 1 |
| Other gene symbols | Cwc1 PRL1 PRP46 PRPF46 TANGO4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000398 | MRNA splicing, via spliceosome | IC | biological_process |
| GO:0003714 | Transcription corepressor activity | TAS | molecular_function |
| GO:0004871 | Signal transducer activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | TAS | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0016607 | Nuclear speck | IEA | cellular_component |
| GO:0071013 | Catalytic step 2 spliceosome | IDA | cellular_component |
| GO:2001141 | Regulation of RNA biosynthetic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9794708560 | 0.0193042400 | 0.9999902473 | 0.2708458955 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5445900843 |
| GSE13712_SHEAR | Down | -0.1603275028 |
| GSE13712_STATIC | Down | -0.0744402357 |
| GSE19018 | Down | -0.7222364955 |
| GSE19899_A1 | Down | -0.2003319792 |
| GSE19899_A2 | Down | -0.2641389475 |
| PubMed_21979375_A1 | Down | -0.5286489114 |
| PubMed_21979375_A2 | Down | -0.4226580284 |
| GSE35957 | Down | -0.1884412249 |
| GSE36640 | Down | -0.2398399935 |
| GSE54402 | Down | -0.0382647222 |
| GSE9593 | Up | 0.0492294843 |
| GSE43922 | Down | -0.0920355883 |
| GSE24585 | Up | 0.0771656523 |
| GSE37065 | Down | -0.1923629655 |
| GSE28863_A1 | Down | -0.2453456771 |
| GSE28863_A2 | Down | -0.2992536209 |
| GSE28863_A3 | Down | -0.5990587570 |
| GSE28863_A4 | Down | -0.2076347948 |
| GSE48662 | Down | -0.3395746482 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT031549 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
