HCSGD entry for PLP1
1. General information
| Official gene symbol | PLP1 |
|---|---|
| Entrez ID | 5354 |
| Gene full name | proteolipid protein 1 |
| Other gene symbols | GPM6C HLD1 MMPL PLP PLP/DM20 PMD SPG2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005198 | Structural molecule activity | TAS | molecular_function |
| GO:0007229 | Integrin-mediated signaling pathway | IEA | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0008366 | Axon ensheathment | TAS | biological_process |
| GO:0010628 | Positive regulation of gene expression | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019911 | Structural constituent of myelin sheath | IEA | molecular_function |
| GO:0022010 | Central nervous system myelination | IEA | biological_process |
| GO:0042759 | Long-chain fatty acid biosynthetic process | IEA | biological_process |
| GO:0043209 | Myelin sheath | IEA | cellular_component |
| GO:0048469 | Cell maturation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2122109722 | 0.9133954409 | 0.8878723573 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2215502919 |
| GSE13712_SHEAR | Down | -0.1894285055 |
| GSE13712_STATIC | Down | -0.1177257695 |
| GSE19018 | Up | 0.1725589148 |
| GSE19899_A1 | Down | -0.0040779386 |
| GSE19899_A2 | Up | 0.1793177927 |
| PubMed_21979375_A1 | Up | 0.2206168407 |
| PubMed_21979375_A2 | Up | 0.2138368225 |
| GSE35957 | Down | -0.1750570265 |
| GSE36640 | Up | 0.0451858863 |
| GSE54402 | Down | -0.0815221394 |
| GSE9593 | Down | -0.2186793672 |
| GSE43922 | Up | 0.0406061841 |
| GSE24585 | Up | 0.3738536476 |
| GSE37065 | Up | 0.5555338185 |
| GSE28863_A1 | Up | 0.1365081406 |
| GSE28863_A2 | Up | 0.0127479415 |
| GSE28863_A3 | Up | 0.3607181698 |
| GSE28863_A4 | Up | 0.1150986821 |
| GSE48662 | Up | 0.0657262496 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
