HCSGD entry for FXYD1
1. General information
| Official gene symbol | FXYD1 |
|---|---|
| Entrez ID | 5348 |
| Gene full name | FXYD domain containing ion transport regulator 1 |
| Other gene symbols | PLM |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005216 | Ion channel activity | IEA | molecular_function |
| GO:0005254 | Chloride channel activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006821 | Chloride transport | TAS | biological_process |
| GO:0006874 | Cellular calcium ion homeostasis | IEA | biological_process |
| GO:0006936 | Muscle contraction | IEA | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0034707 | Chloride channel complex | IEA | cellular_component |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:1902476 | Chloride transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4882314388 | 0.3934228069 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0314749149 |
| GSE13712_SHEAR | Up | 0.0134732435 |
| GSE13712_STATIC | Down | -0.0323295813 |
| GSE19018 | Up | 0.0345001762 |
| GSE19899_A1 | Up | 0.0220551630 |
| GSE19899_A2 | Up | 0.2555839288 |
| PubMed_21979375_A1 | Down | -0.3386782361 |
| PubMed_21979375_A2 | Up | 0.0889308719 |
| GSE35957 | Down | -0.1068071097 |
| GSE36640 | Down | -0.0547403331 |
| GSE54402 | Down | -0.0512133452 |
| GSE9593 | Down | -0.3921739002 |
| GSE43922 | Up | 0.1780095283 |
| GSE24585 | Up | 0.1987364936 |
| GSE37065 | Down | -0.1320481321 |
| GSE28863_A1 | Down | -0.3720964440 |
| GSE28863_A2 | Down | -0.3529414691 |
| GSE28863_A3 | Up | 0.6344394869 |
| GSE28863_A4 | Down | -0.0674364850 |
| GSE48662 | Up | 0.2089239616 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 2889292 | The model quantitatively reproduces LI, PLM, CL and clustering data |
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