HCSGD entry for PANK1


1. General information

Official gene symbolPANK1
Entrez ID53354
Gene full namepantothenate kinase 1
Other gene symbolsPANK
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004594Pantothenate kinase activityIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006766Vitamin metabolic processTASbiological_process
GO:0006767Water-soluble vitamin metabolic processTASbiological_process
GO:0009108Coenzyme biosynthetic processTASbiological_process
GO:0015937Coenzyme A biosynthetic processIEAbiological_process
GO:0015939Pantothenate metabolic processTASbiological_process
GO:0030118Clathrin coatIEAcellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0055037Recycling endosomeIEAcellular_component
GO:0071944Cell peripheryIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.45104702330.17806141100.99999024730.8159391365

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3178097343
GSE13712_SHEARDown-0.2096912122
GSE13712_STATICUp0.2319883621
GSE19018Down-0.3715602186
GSE19899_A1Up0.2271416853
GSE19899_A2Up0.4574563447
PubMed_21979375_A1Down-0.5145984590
PubMed_21979375_A2Up0.0760147848
GSE35957Down-0.5530699954
GSE36640Up0.0212305723
GSE54402Down-0.1349648155
GSE9593Down-0.6960523864
GSE43922Up0.1223607823
GSE24585Down-0.0627853715
GSE37065Up0.0259073872
GSE28863_A1Down-0.2796678711
GSE28863_A2Down-0.0117866756
GSE28863_A3Down-0.2616606000
GSE28863_A4Up0.2641032693
GSE48662Down-0.1269871075

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.