HCSGD entry for PLCL1
1. General information
| Official gene symbol | PLCL1 |
|---|---|
| Entrez ID | 5334 |
| Gene full name | phospholipase C-like 1 |
| Other gene symbols | PLCE PLCL PLDL1 PRIP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004435 | Phosphatidylinositol phospholipase C activity | IEA | molecular_function |
| GO:0004629 | Phospholipase C activity | TAS | molecular_function |
| GO:0004871 | Signal transducer activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006629 | Lipid metabolic process | IEA | biological_process |
| GO:0032228 | Regulation of synaptic transmission, GABAergic | IEA | biological_process |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0050811 | GABA receptor binding | IEA | molecular_function |
| GO:0070679 | Inositol 1,4,5 trisphosphate binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3306025531 | 0.1185596672 | 0.9999902473 | 0.6615664617 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1419582661 |
| GSE13712_SHEAR | Down | -0.9232328771 |
| GSE13712_STATIC | Down | -0.5853116947 |
| GSE19018 | Down | -0.0005826232 |
| GSE19899_A1 | Up | 0.0233059964 |
| GSE19899_A2 | Down | -0.1494005602 |
| PubMed_21979375_A1 | Up | 0.0154053567 |
| PubMed_21979375_A2 | Down | -0.0295996549 |
| GSE35957 | Up | 0.1611105981 |
| GSE36640 | Up | 0.2441348585 |
| GSE54402 | Up | 0.0069279927 |
| GSE9593 | Down | -0.5264976214 |
| GSE43922 | Up | 0.0020598840 |
| GSE24585 | Up | 2.0569245345 |
| GSE37065 | Down | -0.1342082111 |
| GSE28863_A1 | Up | 0.0481720632 |
| GSE28863_A2 | Down | -0.0425176568 |
| GSE28863_A3 | Up | 0.0246725617 |
| GSE28863_A4 | Down | -0.0924505445 |
| GSE48662 | Down | -0.2010598068 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
