HCSGD entry for PLAUR

1. General information

Official gene symbolPLAUR
Entrez ID5329
Gene full nameplasminogen activator, urokinase receptor
Other gene symbolsCD87 U-PAR UPAR URKR
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004872Receptor activityNASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0005788Endoplasmic reticulum lumenTAScellular_component
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0006501C-terminal protein lipidationTASbiological_process
GO:0006928Cellular component movementNASbiological_process
GO:0006935ChemotaxisTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007596Blood coagulationNAS TASbiological_process
GO:0016021Integral component of membraneNAScellular_component
GO:0016255Attachment of GPI anchor to proteinTASbiological_process
GO:0019898Extrinsic component of membraneTAScellular_component
GO:0019899Enzyme bindingIPImolecular_function
GO:0030162Regulation of proteolysisNASbiological_process
GO:0030377Urokinase plasminogen activator receptor activityNASmolecular_function
GO:0031225Anchored component of membraneIEAcellular_component
GO:0038195Urokinase plasminogen activator signaling pathwayNASbiological_process
GO:0042730FibrinolysisTASbiological_process
GO:0043687Post-translational protein modificationTASbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00105949240.99483978570.08769465411.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.9894906488
GSE13712_SHEARUp0.5557532262
GSE13712_STATICUp0.9636000250
GSE19018Up0.3679352935
GSE19899_A1Up0.6177966365
GSE19899_A2Up0.8645254659
PubMed_21979375_A1Up1.1180744834
PubMed_21979375_A2Up0.4403871886
GSE35957Down-0.6106014268
GSE36640Down-0.3424578186
GSE54402Up0.9295291019
GSE9593Up0.6401423556
GSE43922Up0.3958164261
GSE24585Up0.6093696573
GSE37065Up0.6245585137
GSE28863_A1Up0.1474689207
GSE28863_A2Up0.3041098607
GSE28863_A3Up0.0928443610
GSE28863_A4Up0.3512622279
GSE48662Down-0.0443870196

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

AlteplaseDB00009 BTD00050 | BIOD00050
UrokinaseDB00013 BTD00030 | BIOD00030
ReteplaseDB00015 BTD00013 | BIOD00013
AnistreplaseDB00029 BTD00102 | BIOD00102
TenecteplaseDB00031 BTD00019 | BIOD00019
WX-UK1DB05476 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-204-5pMIMAT0000265MIRT005839MicroarrayFunctional MTI (Weak)21282569
hsa-miR-155-5pMIMAT0000646MIRT020661ProteomicsFunctional MTI (Weak)18668040
hsa-miR-16-5pMIMAT0000069MIRT031606ProteomicsFunctional MTI (Weak)18668040
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.