HCSGD entry for PLAGL2


1. General information

Official gene symbolPLAGL2
Entrez ID5326
Gene full namepleiomorphic adenoma gene-like 2
Other gene symbolsZNF900
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptionIDAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityTASmolecular_function
GO:0005634NucleusIBAcellular_component
GO:0006366Transcription from RNA polymerase II promoterIDAbiological_process
GO:0006629Lipid metabolic processIEAbiological_process
GO:0009791Post-embryonic developmentIEAbiological_process
GO:0034378Chylomicron assemblyIBAbiological_process
GO:0043565Sequence-specific DNA bindingIDAmolecular_function
GO:0046872Metal ion bindingIEAmolecular_function
GO:2001244Positive regulation of intrinsic apoptotic signaling pathwayIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.28864324680.71605967100.98687029971.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1104444643
GSE13712_SHEARUp0.0317071772
GSE13712_STATICUp0.2991509952
GSE19018Down-0.1588819076
GSE19899_A1Down-0.0663311939
GSE19899_A2Up0.2232589690
PubMed_21979375_A1Up1.2192651491
PubMed_21979375_A2Up0.5779914612
GSE35957Down-0.1627954861
GSE36640Down-0.8477832769
GSE54402Up0.0977894330
GSE9593Down-0.0549732999
GSE43922Up0.2338497784
GSE24585Down-0.2001706760
GSE37065Up0.0392483141
GSE28863_A1Up0.0103288238
GSE28863_A2Up0.0779492190
GSE28863_A3Up0.1868796274
GSE28863_A4Up0.1256820923
GSE48662Down-0.0584049112

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-let-7b-5pMIMAT0000063MIRT005038MicroarrayFunctional MTI (Weak)17699775
hsa-miR-122-5pMIMAT0000421MIRT023348MicroarrayFunctional MTI (Weak)17612493
hsa-miR-215-5pMIMAT0000272MIRT024808MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026801MicroarrayFunctional MTI (Weak)19074876
hsa-miR-98-5pMIMAT0000096MIRT027836MicroarrayFunctional MTI (Weak)19088304
hsa-miR-24-3pMIMAT0000080MIRT030604MicroarrayFunctional MTI (Weak)19748357
hsa-miR-296-3pMIMAT0004679MIRT038346CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.