HCSGD entry for PITX1
1. General information
| Official gene symbol | PITX1 |
|---|---|
| Entrez ID | 5307 |
| Gene full name | paired-like homeodomain 1 |
| Other gene symbols | BFT CCF LBNBG POTX PTX1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001190 | RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription | IEA | molecular_function |
| GO:0001501 | Skeletal system development | TAS | biological_process |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005667 | Transcription factor complex | IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0009653 | Anatomical structure morphogenesis | TAS | biological_process |
| GO:0014707 | Branchiomeric skeletal muscle development | IEA | biological_process |
| GO:0021983 | Pituitary gland development | IEA | biological_process |
| GO:0035116 | Embryonic hindlimb morphogenesis | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0048625 | Myoblast fate commitment | IEA | biological_process |
| GO:0051216 | Cartilage development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9769529919 | 0.0250171080 | 0.9999902473 | 0.3048180222 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0308000039 |
| GSE13712_SHEAR | Up | 0.0118037656 |
| GSE13712_STATIC | Down | -0.1235366380 |
| GSE19018 | Down | -0.0811539443 |
| GSE19899_A1 | Down | -1.9521286731 |
| GSE19899_A2 | Down | -0.8387248215 |
| PubMed_21979375_A1 | Down | -0.5888148970 |
| PubMed_21979375_A2 | Up | 0.0506911767 |
| GSE35957 | Down | -0.5296402301 |
| GSE36640 | Up | 0.0869153646 |
| GSE54402 | Down | -0.3666973858 |
| GSE9593 | Up | 0.1876999929 |
| GSE43922 | Down | -0.1588827524 |
| GSE24585 | Down | -0.2238480953 |
| GSE37065 | Up | 0.0423048028 |
| GSE28863_A1 | Down | -0.1465765829 |
| GSE28863_A2 | Down | -0.2010205953 |
| GSE28863_A3 | Down | -0.0288272388 |
| GSE28863_A4 | Down | -0.1830534225 |
| GSE48662 | Up | 0.1043387504 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-331-3p | MIMAT0000760 | MIRT043542 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044749 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045636 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049789 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
